A well-calibrated and validated model of observed trends will allow possible extensions to secondary objectives, which can include projecting the impact of new interventions on future trends, as well as designing optimal cancer control strategies.
Provider-level data To understand how the implementation strategies and the study are perceived by the people who work at the health center and to assess whether strategies directed at providers actually reached them, we will also conduct brief, anonymous surveys of health center employees.
Validity of self-reported colorectal cancer screening behavior. Awardees will retain custody of and have primary rights to the models and model results developed under these awards, subject to Government rights of access consistent with current HHS, PHS, and NIH policies. Prevalence rates are estimated based on our experiences with similar patient populations, local BRFSS data, and published screening rates.
As such, the early outcomes and formative work involved in this research inform the procedures A proposal for cancer intervention in the latter activities.
Where possible, we start with a known contact; in other sites, the health center Chief Executive Officer or Chief Medical Officer is identified from websites. Working Groups Meet at least twice a year.
A Model of the population impact of the introduction of new therapies using estimates of the impact of these therapies in controlled settings and population dissemination patterns e. The study team considered using chart reviews as the primary outcome.
The total project period for applications submitted in response to the present RFA may not exceed four years.
Is the investigator appropriately trained and well suited to carry out this work? As part of the initial merit review, a process will be used by the initial review group in which applications receive a written critique and undergo a process in which only those applications deemed to have the highest scientific merit, generally the top half of the applications under review, will be discussed assigned a priority score, and receive a second level review by the National Cancer Advisory Board.
Recruitment and retention of African American elders into community based research: Reviewers are cautioned that their anonymity may be compromised when they directly access an Internet site.
A scientist administrator from the NCI extramural staff, the Program Director, will not only provide normal stewardship for the U01 grants awarded under this RFA, but will also be involved in the scientific coordination and collaboration within the Network and will coordinate interaction between the research groups.
We will aim to conduct at least two interviews per participating site. Awardees will be expected to engage in efforts coordinated by the Working Groups for calibration, validation, and comparison of model results. Our research design is aimed at testing the effect of an implementation intervention to increase colorectal cancer screening, and at the same time assess the viability and challenge of translating evidence-based strategies into diverse settings.
Applicants may wish to place data collected under this RFA in a public archive, which can provide protections for the data and manage the distribution for an indefinite period of time. Review Criteria The goals of NIH-supported research are to advance our understanding of biological systems, improve the control of disease, and enhance health.
At most sites, the research team will work with the CHC to randomly select eligible patients and mail letters of invitation to potential participants. In addition, investigators should state their willingness to participate in joint meetings, to share methods and data resources, and to embark on collaborative efforts to decide overall research direction.
Is this a new or existing model? We recognize that some sites may have smaller patient populations and that retaining participants over the course of the month study may be harder when working with underserved populations whose contact information may change during the study period.
This second round of funding for CISNET will be limited to applications focusing on prostate, colorectal, and lung cancers.
Failure to use this label could result in delayed processing of the application such that it may not reach the review committee in time for review. Euclid Ave, Campus BoxSt.
We will use a chart audit on a subset of sites for further verification of self-report in this population see section entitled Data collection — Patient-level data. J Med Screen ;6: Cancer risk factors among those aged 65 and older: Patients are recruited by mailed invitation letter from the health center about the study and giving them the opportunity to opt out.
New investigators will be expected to join in the ongoing collaborative activities already underway. The opportunity to clarify any issues or questions from potential applicants is welcome. It is anticipated that several modeling centers will submit applications for more than one cancer site.
The long-term goal is to reduce CRC disparities by developing sustainable and disseminable implementation approaches that will effectively promote informed decisions about CRC screening across a variety of settings, particularly those considered underserved.
D Use discrepancies between modeled and observed population trends to study the community effectiveness of interventions e. The investigator who is designated by the applicant organization to direct the project to be supported by the U01 grant.
Evidence from seven studies. Primary care practice-based research networks: In conjunction with the development of these models, there have been various methodologic spin-offs that have broad uses in a variety of modeling settings.
These studies will often involve extrapolation of results of controlled cancer intervention studies to estimates of U.
Most interventions have been tested in structured and well-resourced settings [ 19 - 22 ]. All authors helped revise the manuscript and reviewed the final version.
J Natl Cancer Inst Monogr.Intervention trials in cancer survivors play an important and growing role in complementing the wealth of knowledge obtained from observational studies about how lifestyle can improve clinical, physiological and psychological outcomes.
Dr. Bristow has pioneered advanced techniques for the management of a variety of gynecological cancers. Recognized internationally as a leading expert in ovarian, fallopian tube, primary peritoneal and endometrial cancers, he is the author of five books on ovarian cancer and he has published extensively in the field of ovarian cancer research.
In the present study, we reviewed grant proposals, funded by the National Cancer Institute, to provide a prospective view of how investigators plan to use theory in intervention research.
We identified seven core elements to describe use of. Example proposal: Global Health Perceptions and Impact of HIV-Related Stigma in Low-income Communities of Urban Addis Ababa. /AIDS is a highly stigmatized disease and although the presence of stigma is widely acknowledged, practical methods of intervention are rarely documented or analyzed for outcome and effectiveness.
Literature reviews. SAMPLE GRANT GUIDELINES detection and intervention, research into dietary links to cancer, behavioral/educational aspects of cancer relevance of this proposal to cancer prevention/early detection.
Research Plan Statement of Significance (1 page): A statement of the significance of your proposed project with. Cancer Prevention and Control: Skin Cancer Prevention The Guide to Community Preventive Services (The Community Guide) is an essential resource for people.Download